Eine Überprüfung der Methadontabletten zur Schmerzbehandlung
Eine Überprüfung der Methadontabletten zur Schmerzbehandlung
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Methadone contains methadone, a mu-agonist opioid with an abuse liability similar to other opioid agonists and is a Schedule II controlled substance. Methadone and other opioids used in analgesia have the potential for being abused and are subject to criminal diversion.
Pregnancy – The disposition of oral methadone has been studied in approximately 30 pregnant patients in 2nd and 3rd trimesters. Elimination of methadone welches significantly changed in pregnancy. Total body clearance of methadone was increased hinein pregnant patients compared to the same patients postpartum or to non-pregnant opioid-dependent women. The Am ende gelegen half-life of methadone is decreased during 2nd and 3rd trimesters.
Don’t put this medication in your car’s glove compartment or leave it hinein the car. Beryllium sure to avoid doing this when the weather is very hot or very cold.
The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
It is very important that you take methadone hydrochloride tablets exactly as your doctor has prescribed. Talk to your doctor about your pain. Your doctor can decide if your methadone hydrochloride tablets dose needs to be changed.
The use of methadone has not been extensively evaluated hinein patients with hepatic insufficiency. Methadone is metabolized in the liver and patients with liver impairment may be at risk of accumulating methadone after multiple dosing.
Upon discontinuation of phenytoin, the incidence of withdrawal symptoms decreased and methadone exposure increased to a level comparable to that prior to phenytoin administration.
Pediatric – The pharmacokinetics of methadone have not been Methadontabletten ohne Rezept online evaluated rein the pediatric Fortpflanzungsgemeinschaft.
Do not take any medicine while using methadone hydrochloride tablets until you have first talked to your doctor or pharmacist. They will be able to tell you if it is safe to take other medicines while you are using methadone hydrochloride tablets.
Patients should be cautioned that methadone, like all opioids, may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks such as driving or operating machinery.
The Satz at which methadone is decreased should Beryllium determined separately for each patient. The dose of methadone can be decreased on a daily Lager or at 2-day intervals, but the amount of intake should remain sufficient to keep withdrawal symptoms at a tolerable level. Hinein hospitalized patients, a daily reduction of 20% of the total daily dose may be tolerated. Hinein ambulatory patients, a somewhat slower schedule may Beryllium needed.
What are Methadone Hydrochloride Tablets? Methadone hydrochloride tablets are a prescription medicine that contains methadone, which is a narcotic pain medicine similar to morphine.
The following drug interactions were reported following coadministration of methadone with inducers of cytochrome P450 enzymes:
For people with breathing problems: This drug can cause breathing problems. It can also worsen breathing problems you already have.